Understanding life as a consequence of the evolution of the matter and energy in the Universe and, independently where it begun, other key questions are universal like: which was the prebiotic chemistry that led to the first complex polymers? How the different molecular species behaved and survived? How they replicated and acquired the capacity to storage and transmit information? How they evolved and adapted to the environment? How can we distinguish and detect true biomolecules (molecular biomarkers) from other non-biological organic molecules?